Article
Pattern of p53 gene mutations in breast cancers of women of the midwestern United States.
Journal of the National Cancer Institute - 19 Feb 1992
Sommer S S, Cunningham J, McGovern R M, Saitoh S, Schroeder J J, Wold L E, Kovach J S
Abstract excerpt
BACKGROUND: Mutation in the p53 gene is the most common genetic lesion in human cancers. The pattern of mutation in the p53 gene differs among cancers and may be a useful epidemiological tool for identification of factors contributing to carcinogenesis. PURPOSE: Our purpose was to determine if the pattern of p53 mutation in breast carcinomas in our population of women residing in the midwestern region of the...
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