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Article

Power loss for multiallelic transmission/disequilibrium test when errors introduced: GAW11 simulated data.

Genetic epidemiology - 1 Jan 1999

Gordon D, Matise T C, Heath S C, Ott J

Abstract excerpt

Many researchers are considering the use of transmission/disequilibrium tests (TDT) for trios of genotypes (father, mother, child) as a method for localizing genes associated with complex diseases. We evaluate the effect of random errors (allele changes) in trios on the power to detect linkage. For a marker in the simulated data set, one allele is associated with the fictitious disease in a certain subpopulation....

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PMID: 10597497
DOI: 10.1002/gepi.1370170795

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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