Article
Precision and type I error rate in the presence of genotype errors and missing parental data: a comparison between the original transmission disequilibrium test (TDT) and TDTae statistics.
BMC genetics - 30 Dec 2005
Barral Sandra, Haynes Chad, Levenstien Mark A, Gordon Derek
Abstract excerpt
BACKGROUND: Two factors impacting robustness of the original transmission disequilibrium test (TDT) are: i) missing parental genotypes and ii) undetected genotype errors. While it is known that independently these factors can inflate false-positive rates for the original TDT, no study has conside...
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