Article
A transmission/disequilibrium test that allows for genotyping errors in the analysis of single-nucleotide polymorphism data.
American journal of human genetics - 1 Aug 2001
Gordon D, Heath S C, Liu X, Ott J
Abstract excerpt
The present study assesses the effects of genotyping errors on the type I error rate of a particular transmission/disequilibrium test (TDT(std)), which assumes that data are errorless, and introduces a new transmission/disequilibrium test (TDT(ae)) that allows for random genotyping errors. We evaluate the type I error rate and power of the TDT(ae) under a variety of simulations and perform a power comparison...
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