Article
An analytic solution to single nucleotide polymorphism error-detection rates in nuclear families: implications for study design.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2000
Gordon D, Leal S M, Heath S C, Ott J
Abstract excerpt
Recently, there has been increased interest in using Single Nucleotide Polymorphisms (SNPs) as a method for detecting genes for complex traits. SNPs are diallelic markers that have the potential to be inexpensively produced using chip technology. It has been suggested that SNPs will be beneficial in study designs that utilize trio data (father, mother, child). In our previous work, we calculated the probability...
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