Article
Haplotype sharing transmission/disequilibrium tests that allow for genotyping errors.
Genetic epidemiology - 1 May 2005
Sha Qiuying, Dong Jianping, Jiang Renfang, Chen Huann-Sheng, Zhang Shuanglin
Abstract excerpt
The present study introduces new Haplotype Sharing Transmission/Disequilibrium Tests (HS-TDTs) that allow for random genotyping errors. We evaluate the type I error rate and power of the new proposed tests under a variety of scenarios and perform a power comparison among the proposed tests, the HS-TDT and the single-marker TDT. The results indicate that the HS-TDT shows a significant increase in type I error when...
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