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Article

Undetected genotyping errors cause apparent overtransmission of common alleles in the transmission/disequilibrium test.

American journal of human genetics - 1 Mar 2003

Mitchell Adele A, Cutler David J, Chakravarti Aravinda

Abstract excerpt

The transmission/disequilibrium test (TDT), a family-based test of linkage and association, is a popular and intuitive statistical test for studies of complex inheritance, as it is nonparametric and robust to population stratification. We carried out a literature search and located 79 significant TDT-derived associations between a microsatellite marker allele and a disease. Among these, there were 31 (39%) in...

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Identifiers

PMID: 12587097
DOI: 10.1086/368203
PMCID: PMC1180236

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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