Article
Reaper-induced dissociation of a Scythe-sequestered cytochrome c-releasing activity.
The EMBO journal - 15 Oct 1999
Thress K, Evans E K, Kornbluth S
Abstract excerpt
Reaper is a potent apoptotic inducer critical for programmed cell death in the fly Drosophila melanogaster. While Reaper homologs from other species have not yet been reported, ectopic expression of Reaper in cells of vertebrate origin can also trigger apoptosis, suggesting that Reaper-responsive pathways are likely to be conserved. We recently reported that Reaper-induced mitochondrial cytochrome c release and...
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