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Article

Cell killing by the Drosophila gene reaper.

Science (New York, N.Y.) - 9 Feb 1996

White K, Tahaoglu E, Steller H

Abstract excerpt

The reaper gene (rpr) is important for the activation of apoptosis in Drosophila. To investigate whether rpr expression is sufficient to induce apoptosis, transgenic flies were generated that express rpr complementary DNA or the rpr open reading frame in cells that normally live. Transcription of rpr from a heat-inducible promoter rapidly caused wide-spread ectopic apoptosis and organismal death. Ectopic...

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Identifiers

PMID: 8628996
DOI: 10.1126/science.271.5250.805

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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