Article
Cell killing by the Drosophila gene reaper.
Science (New York, N.Y.) - 9 Feb 1996
White K, Tahaoglu E, Steller H
Abstract excerpt
The reaper gene (rpr) is important for the activation of apoptosis in Drosophila. To investigate whether rpr expression is sufficient to induce apoptosis, transgenic flies were generated that express rpr complementary DNA or the rpr open reading frame in cells that normally live. Transcription of...
Topics
- Animals
- Animals, Genetically Modified
- Apoptosis
- Caspase 1
- Cysteine Endopeptidases
- DNA, Complementary
- Drosophila
- Drosophila Proteins
- Gene Dosage
- Gene Expression
- Genes, Insect
- Hot Temperature
- Inhibitor of Apoptosis Proteins
- Mutation
- Open Reading Frames
- Peptides
- Photoreceptor Cells, Invertebrate
- Transgenes