Article
Genetic control of programmed cell death in Drosophila.
Science (New York, N.Y.) - 29 Apr 1994
White K, Grether M E, Abrams J M, Young L, Farrell K, Steller H
Abstract excerpt
A gene, reaper (rpr), that appears to play a central control function for the initiation of programmed cell death (apoptosis) in Drosophila was identified. Virtually all programmed cell death that normally occurs during Drosophila embryogenesis was blocked in embryos homozygous for a small deletion that includes the reaper gene. Mutant embryos contained many extra cells and failed to hatch, but many other aspects...
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