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Article

Genetic control of programmed cell death in Drosophila.

Science (New York, N.Y.) - 29 Apr 1994

White K, Grether M E, Abrams J M, Young L, Farrell K, Steller H

Abstract excerpt

A gene, reaper (rpr), that appears to play a central control function for the initiation of programmed cell death (apoptosis) in Drosophila was identified. Virtually all programmed cell death that normally occurs during Drosophila embryogenesis was blocked in embryos homozygous for a small deleti...

Topics

Amino Acid Sequence
Animals
Apoptosis
Base Sequence
Cloning, Molecular
DNA Primers
Drosophila
Drosophila Proteins
Embryo, Nonmammalian
Genes, Insect
Models, Genetic
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Nervous System

Neurons

Peptides

Source

Identifiers

PMID: 8171319
DOI: 10.1126/science.8171319

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8171319-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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