Article
Apoptotic proteins Reaper and Grim induce stable inactivation in voltage-gated K+ channels.
Proceedings of the National Academy of Sciences of the United States of America - 29 Sept 1998
Avdonin V, Kasuya J, Ciorba M A, Kaplan B, Hoshi T, Iverson L
Abstract excerpt
Drosophila genes reaper, grim, and head-involution-defective (hid) induce apoptosis in several cellular contexts. N-terminal sequences of these proteins are highly conserved and are similar to N-terminal inactivation domains of voltage-gated potassium (K+) channels. Synthetic Reaper and Grim N te...
Topics
- Amino Acid Sequence
- Animals
- Apoptosis
- Base Sequence
- DNA Primers
- Drosophila
- Drosophila Proteins
- Female
- Genes, Insect
- Insect Proteins
- Molecular Sequence Data
- Mutation
- Neuropeptides
- Oocytes
- Peptide Fragments
- Peptides
- Potassium Channel Blockers
- Potassium Channels