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Article

Apoptotic proteins Reaper and Grim induce stable inactivation in voltage-gated K+ channels.

Proceedings of the National Academy of Sciences of the United States of America - 29 Sept 1998

Avdonin V, Kasuya J, Ciorba M A, Kaplan B, Hoshi T, Iverson L

Abstract excerpt

Drosophila genes reaper, grim, and head-involution-defective (hid) induce apoptosis in several cellular contexts. N-terminal sequences of these proteins are highly conserved and are similar to N-terminal inactivation domains of voltage-gated potassium (K+) channels. Synthetic Reaper and Grim N terminus peptides induced fast inactivation of Shaker-type K+ channels when applied to the cytoplasmic side of the...

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Identifiers

PMID: 9751729
DOI: 10.1073/pnas.95.20.11703
PMCID: PMC21704

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Apoptotic proteins Reaper and Grim induce stable inactivation in voltage-gated K+ channels.PMID 9751729Read ↗

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Diverse domains of THREAD/DIAP1 are required to inhibit apoptosis induced by REAPER and HID in Drosophila.Semantic proximity Read ↗

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Cell killing by the Drosophila gene reaper.Semantic proximity Read ↗

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Dredd, a novel effector of the apoptosis activators reaper, grim, and hid in Drosophila.Semantic proximity Read ↗

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