Article
Dredd, a novel effector of the apoptosis activators reaper, grim, and hid in Drosophila.
Developmental biology - 15 Sept 1998
Chen P, Rodriguez A, Erskine R, Thach T, Abrams J M
Abstract excerpt
Caspases are widely conserved proteases considered to be essential effectors of apoptosis. We identified a novel Drosophila gene, dredd, which shares extensive homology to all members of the caspase gene family. Cells specified for programmed death in development exhibit a striking accumulation o...
Topics
- Amino Acid Sequence
- Animals
- Apoptosis
- Caspases
- Cloning, Molecular
- Drosophila
- Drosophila Proteins
- Gene Expression Regulation
- In Situ Hybridization
- Insect Proteins
- Microscopy, Electron, Scanning
- Molecular Sequence Data
- Mutation
- Neuropeptides
- Peptides
- RNA, Messenger
- Sequence Analysis, DNA
- Sequence Homology, Amino Acid