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Article

Characterization of reaper- and FADD-induced apoptosis in a lepidopteran cell line.

Molecular and cellular biology - 1 Feb 1997

Vucic D, Seshagiri S, Miller L K

Abstract excerpt

Expression of the reaper gene (rpr) correlates with the initiation of apoptosis in Drosophila melanogaster. Transient expression of rpr in the lepidopteran SF-21 cell line induced apoptosis displaying nuclear condensation and fragmentation, oligonucleosomal ladder formation, cell surface blebbing, and apoptotic body formation. Inhibitors of ICE-family proteases p35 and crmA, as well as members of the iap class of...

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Identifiers

PMID: 9001220
DOI: 10.1128/MCB.17.2.667
PMCID: PMC231792

Genes

FADD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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