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The Drosophila caspase DRONC is required for metamorphosis and cell death in response to irradiation and developmental signals.

Mechanisms of development - 1 Jul 2005

Waldhuber Markus, Emoto Kazuo, Petritsch Claudia

Abstract excerpt

Cell death is essential for eliminating excess cells during development as well as removing damaged cells. While multiple conserved apoptosis pathways involving different cascades of caspases, which are cysteine proteases, have been identified, their regulation in the context of a developing organism is not very well understood. Expression of the Drosophila caspase-9 homolog, DRONC, can be induced by ecdysone, a...

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PMID: 15922568
DOI: 10.1016/j.mod.2005.04.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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