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Article

The RHG motifs of Drosophila Reaper and Grim are important for their distinct cell death-inducing abilities.

Mechanisms of development - 1 Apr 2001

Wing J P, Schwartz L M, Nambu J R

Abstract excerpt

Reaper, Hid, and Grim are three Drosophila cell death activators that each contain a conserved NH(2)-terminal Reaper, Hid, Grim (RHG) motif. We have analyzed the importance of the RHG motifs in Reaper and Grim for their different abilities to activate cell death during development. Analysis of chimeric R/Grim and G/Reaper proteins indicated that the Reaper and Grim RHG motifs are functionally distinct and help to...

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PMID: 11287192
DOI: 10.1016/s0925-4773(01)00316-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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