Article
Human chromosomes 11p15 and 4p12 and alcohol dependence: possible association with the GABRB1 gene.
American journal of medical genetics - 15 Oct 1999
Parsian A, Zhang Z H
Abstract excerpt
To determine the role of genes in the chromosomal regions 11p15 and 4p12 in the development of alcohol dependence, a sample of alcoholics (n = 133) and normal controls (n = 89) were screened using polymorphisms in the dopamine D4 receptor (DRD4), tyrosine hydroxylase (TH), and GABA receptor beta1 (GABRbeta1) genes. Comparison of total alcoholics with normal controls for GABRbeta1 gene was highly significant (p =...
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