Article
No association of the GABAA receptor genes on chromosome 5 with alcoholism in the collaborative study on the genetics of alcoholism sample.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jan 2005
Dick Danielle M, Edenberg Howard J, Xuei Xiaoling, Goate Alison, Hesselbrock Victor, Schuckit Marc, Crowe Raymond, Foroud Tatiana
Abstract excerpt
A substantial body of literature suggests that gamma-aminobutyric acid (GABA) may be involved in the neurochemical pathways contributing to alcohol use and related disorders. Chromosome 5 contains a cluster of GABA(A) receptor genes, GABRA1, GABRA6, GABRB2, and GABRG2, which have been among the most extensively studied in relation to alcohol use. These studies have yielded mixed results. Using data from large,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
