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Article

GABRG1 and GABRA2 variation associated with alcohol dependence in African Americans.

Alcoholism, clinical and experimental research - 1 Apr 2012

Ittiwut Chupong, Yang Bao-Zhu, Kranzler Henry R, Anton Raymond F, Hirunsatit Rungnapa, Weiss Roger D, Covault Jonathan, Farrer Lindsay A, Gelernter Joel

Abstract excerpt

BACKGROUND: GABRG1 and GABRA2, genes that encode the γ1 and α2 subunits, respectively, of the GABA-A receptor, are located in a cluster on chromosome 4p. Association of alcohol dependence (AD) with markers located at the 3' region of GABRA2 has been replicated in several studies, but recent studies suggested the possibility that the signal may be attributable to the adjacent gene, GABRG1, located 90 kb distant in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21919924
DOI: 10.1111/j.1530-0277.2011.01637.x
PMCID: PMC3250564

Genes

GABRA2
GABRG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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