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Article

Gamma-aminobutyric acid receptor genes and nicotine dependence: evidence for association from a case-control study.

Addiction (Abingdon, England) - 1 Jun 2008

Agrawal Arpana, Pergadia Michele L, Saccone Scott F, Hinrichs Anthony L, Lessov-Schlaggar Christina N, Saccone Nancy L, Neuman Rosalind J, Breslau Naomi, Johnson Eric, Hatsukami Dorothy, Montgomery Grant W, Heath Andrew C, Martin Nicholas G, Goate Alison M, Rice John P, Bierut Laura J, Madden Pamela A F

Abstract excerpt

AIMS: The gamma-aminobutyric acid receptor A (GABRA) gene clusters on chromosomes 4 and 5 have been examined previously for their association with alcohol and drug dependence phenotypes. Compelling evidence suggests that GABRA2 is associated with alcohol and drug dependence. However, no study has investigated whether genes in the GABA(A) gene clusters are associated with nicotine dependence, an important...

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Source

Identifiers

PMID: 18482426
DOI: 10.1111/j.1360-0443.2008.02236.x

Genes

GABRA2
GABBR2
GABRA4
GABRE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Gamma-aminobutyric acid receptor genes and nicotine dependence: evidence for association from a case-control study.PMID 18482426Read ↗

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