Article
Adiposity is associated with p53 gene mutations in breast cancer.
Breast cancer research and treatment - 1 Oct 2015
Ochs-Balcom Heather M, Marian Catalin, Nie Jing, Brasky Theodore M, Goerlitz David S, Trevisan Maurizio, Edge Stephen B, Winston Janet, Berry Deborah L, Kallakury Bhaskar V, Freudenheim Jo L, Shields Peter G
Abstract excerpt
Mutations in the p53 gene are among the most frequent genetic events in human cancer and may be triggered by environmental and occupational exposures. We examined the association of clinical and pathological characteristics of breast tumors and breast cancer risk factors according to the prevalence and type of p53 mutations. Using tumor blocks from incident cases from a case-control study in western New York, we...
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