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Article

Characterization of p53 gene mutations in a Brazilian population with oral squamous cell carcinomas.

International journal of oncology - 1 Feb 2004

Chaves Anna C M, Cherubini Karen, Herter Nilton, Furian Roque, Santos Diogenes S, Squier Christopher, Domann Frederick E

Abstract excerpt

Mutations in the p53 tumor suppressor gene are present in approximately 50% of all human cancers. We sought to determine the frequency and type of p53 mutations in squamous cell carcinomas (SCC) of the oral cavity in a Brazilian population. To identify p53 mutations we used PCR-SSCP in tumor tissue microdissected from paraffin- embedded and from fresh-frozen sections followed by direct sequencing of SSCP bands...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 14719105

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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