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Article

Correlation between p53 immunostaining patterns and gene sequence mutations in breast carcinoma.

Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Sept 1996

Visscher D W, Sarkar F H, Shimoyama R K, Crissman J D

Abstract excerpt

We performed p53 immunostaining in 82 invasive breast carcinomas by using two commercially available antibodies, one of which (DO7) was employed in formalin-fixed paraffin-embedded sections. The other antibody (PAb1801) was evaluated in corresponding acetone-fixed cryostat sections. A greater percent of cases were immunostained with DO7 compared to PAb1801 (52% vs 33%); however, the staining was more often...

Topics

Antibodies, Monoclonal
Biomarkers
Breast Neoplasms
Carcinoma, Ductal, Breast
DNA, Neoplasm
Genes, p53
Humans
Immunohistochemistry
Indicators and Reagents
Mutation
Polymorphism, Single-Stranded Conformational

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Staining and Labeling

Tumor Suppressor Protein p53

Source

Identifiers

PMID: 8866232
DOI: 10.1097/00019606-199609000-00007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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