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Article

Absence of APC gene mutation in the mutation cluster region in hepatocellular carcinoma.

Cancer letters - 11 Dec 1998

Chen T C, Hsieh L L, Ng K F, Jeng L B, Chen M F

Abstract excerpt

APC gene mutations have been demonstrated not only in colorectal carcinoma but also in a variety of human cancers. To define the possible role of mutations of the APC gene in hepatocarcinogenesis, we examined 46 pairs of hepatocellular carcinomas and corresponding non-tumorous liver tissue by polymerase chain reaction and single strand conformation polymorphism. All 46 hepatocellular carcinomas had no altered...

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Share to Carcinoma, Hepatocellular
Share to DNA, Neoplasm
Share to Genes, APC

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Liver Neoplasms

Share to Loss of Heterozygosity

Share to Polymorphism, Single-Stranded Conformational

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Share to Tumor Suppressor Proteins

Source

Identifiers

PMID: 10381126
DOI: 10.1016/s0304-3835(98)00238-9

Genes

APC
MCC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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