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Article

Somatic mutations of the APC gene in sporadic hepatoblastomas.

Cancer research - 15 Jul 1996

Oda H, Imai Y, Nakatsuru Y, Hata J, Ishikawa T

Abstract excerpt

Hepatoblastoma is a rare hepatic malignancy that occurs in children with an average age of 2 or 3 years and is known to be one of the extracolonic manifestations of familial adenomatous polyposis. Only a single hepatoblastoma with a germ-line mutation of the adenomatous polyposis coli (APC) gene has been reported thus far. To elucidate the possible roles of APC gene alterations in sporadic hepatoblastomas, we...

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Identifiers

PMID: 8764128

Genes

APC
MCC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Somatic mutations of the APC gene in sporadic hepatoblastomas.PMID 8764128Read ↗

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Somatic mutations of beta-catenin play a crucial role in the tumorigenesis of sporadic hepatoblastoma.Semantic proximity Read ↗

Absence of APC gene mutation in the mutation cluster region in hepatocellular carcinoma.Semantic proximity Read ↗

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