Article
Allelic deletions of MCC/APC and p53 are frequent late events in human gastric carcinogenesis.
Gastroenterology - 1 Jun 1994
Rhyu M G, Park W S, Jung Y J, Choi S W, Meltzer S J
Abstract excerpt
BACKGROUND/AIMS: Frequent allelic deletion affecting the mutated in colon cancer/adenomatous polyposis coli (MCC/APC) and p53 tumor suppressor gene loci has been reported in human cancers. However, simultaneous correlative analyses of these two abnormalities or their timing in gastric tumorigenesis have not been performed. METHODS: To ascertain the relation between and timing of allelic deletions of MCC/APC and...
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