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Article

Molecular analysis of the adenomatous polyposis coli gene in sarcomas, hematological malignancies and noncolonic, neoplastic tissues.

Journal of molecular medicine (Berlin, Germany) - 1 Feb 1997

Wada M, Miller C W, Yokota J, Lee E, Mizoguchi H, Koeffler H P

Abstract excerpt

Somatic mutations of the adenomatous polyposis coli (APC) gene have been frequently found in sporadic colorectal tumors, and the frequency of such mutations remain constant as tumors progress from benign adenomas to malignant cancers. Thus the mutations of the APC gene may have a major role in the early development of sporadic colorectal tumors. Whether inactivation of the APC gene accounts for other types of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 9083931
DOI: 10.1007/s001090050098

Genes

APC

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Molecular analysis of the adenomatous polyposis coli gene in sarcomas, hematological malignancies and noncolonic, neoplastic tissues.PMID 9083931Read ↗

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APC mutations and other genetic and epigenetic changes in colon cancer.Semantic proximity Read ↗

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