Article
Mutations of the APC (adenomatous polyposis coli) gene.
Human mutation - 1 Jan 1993
Nagase H, Nakamura Y
Abstract excerpt
Several investigators have reported germline mutations of the APC gene in patients with familial adenomatous polyposis (FAP) as well as somatic mutations in tumors developed in digestive organs (stomach, pancreas, colon, and rectum). Those results provide evidence that inactivation of the APC gen...
Topics
- Adenomatous Polyposis Coli
- Base Sequence
- Colorectal Neoplasms
- Humans
- Molecular Sequence Data
- Mutation
- Point Mutation