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Article

Mutational analysis of the p73 gene in human breast cancers.

International journal of cancer - 21 Jun 1999

Shishikura T, Ichimiya S, Ozaki T, Nimura Y, Kageyama H, Nakamura Y, Sakiyama S, Miyauchi M, Yamamoto N, Suzuki M, Nakajima N, Nakagawara A

Abstract excerpt

In primary breast cancer, mutations of the p53 tumor suppressor gene lead to loss of growth-suppressive properties and poor outcome. Recently, a p53-related gene, termed p73, has been cloned and its gene product possesses a function similar to p53. p73 has been mapped at chromosome 1p36.3, a region frequently deleted in breast cancer, neuroblastoma and other malignancies. To elucidate the functional significance...

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Identifiers

PMID: 10371354
DOI: 10.1002/(sici)1097-0215(19990621)84:3<321::aid-ijc21>3.0.co;2-s

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Research trail→

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Mutational analysis of the p73 gene in human breast cancers.PMID 10371354Read ↗

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Infrequent somatic mutations of the p73 gene in various human cancers.Semantic proximity Read ↗

Mutational analysis of the p73 gene localized at chromosome 1p36.3 in colorectal carcinomas.Semantic proximity Read ↗

p73, a gene related to p53, is not mutated in esophageal carcinomas.Semantic proximity Read ↗

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Absence of mutation of the p73 gene localized at chromosome 1p36.3 in hepatocellular carcinoma.Semantic proximity Read ↗

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Genomic and allelic expression status of the p73 gene in human neuroblastoma.Semantic proximity Read ↗

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