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Article

Lack of p73 mutations and late occurrence of p73 allelic deletions in melanoma tissues and cell lines.

International journal of cancer - 12 Aug 1999

Schittek B, Sauer B, Garbe C

Abstract excerpt

A novel gene, termed p73 with significant homology to p53, has been identified at 1p36, a chromosomal region which is frequently deleted in malignant melanoma. To determine whether p73 is involved in melanoma development we analyzed 8 benign melanocytic nevi, 17 primary melanomas, 34 melanoma met...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10404074
DOI: 10.1002/(sici)1097-0215(19990812)82:4<583::aid-ijc18>3.0.co;2-g

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-10404074-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lack of p73 mutations and late occurrence of p73 allelic deletions in melanoma tissues and cell lines.PMID 10404074Read ↗

Loss of expression or mutations in the p73 tumour suppressor gene are not involved in the pathogenesis of malignant melanomas.Semantic proximity Read ↗

Allelic loss at the p73 locus (1p36.33) is infrequent in malignant melanoma.Semantic proximity Read ↗

Mutational analysis of the p73 gene in human breast cancers.Semantic proximity Read ↗

p73 gene alterations and expression in primary oral and laryngeal squamous carcinomas.Semantic proximity Read ↗

p53 expression is rare in cutaneous melanomas.Semantic proximity Read ↗

p73 mutations are not detected in sporadic and hereditary breast cancer.Semantic proximity Read ↗

Analysis of p53 in human cutaneous melanoma cell lines.Semantic proximity Read ↗

Expression level, allelic origin, and mutation analysis of the p73 gene in neuroblastoma tumors and cell lines.Semantic proximity Read ↗

Mutation analysis of P73 and TP53 in Merkel cell carcinoma.Semantic proximity Read ↗

Absence of p53 gene mutations in cutaneous melanoma.Semantic proximity Read ↗

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers.Semantic proximity Read ↗

p73, a gene related to p53, is not mutated in esophageal carcinomas.Semantic proximity Read ↗

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