Article
p73 gene alterations and expression in primary oral and laryngeal squamous carcinomas.
Carcinogenesis - 1 May 2001
El-Naggar A K, Lai S, Clayman G L, Mims B, Lippman S M, Coombes M, Luna M A, Lozano G
Abstract excerpt
p73, a recently identified gene, maps to chromosome region 1p36.3, which is frequently deleted in a variety of solid tumors. Although the gene shares sequence and functional homologies with p53, its suppressor function has not been proven. We investigated for the first time the genetic and expres...
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