Expression level, allelic origin, and mutation analysis of the p73 gene in neuroblastoma tumors and cell lines.

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Article

Expression level, allelic origin, and mutation analysis of the p73 gene in neuroblastoma tumors and cell lines.

Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Nov 1998

Kovalev S, Marchenko N, Swendeman S, LaQuaglia M, Moll U M

Abstract excerpt

The novel p73 gene is a structural and, in overexpression systems, functional p53 homologue. p73 resides on chromosome 1p36.33 within a commonly deleted region in neuroblastoma (NB) and other human tumors. To evaluate p73's candidacy for a NB suppressor, we analyzed 28 primary NB tumors, 14 NB ce...

Topics

Alleles
DNA-Binding Proteins
Gene Expression
Genes, Tumor Suppressor
Humans
Mutation
Neuroblastoma
Nuclear Proteins
Tumor Cells, Cultured
Tumor Protein p73
Tumor Suppressor Proteins

Source

Open in PubMed

Identifiers

PMID: 9831242

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9831242-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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