Article
Rho controls actin cytoskeletal assembly in renal epithelial cells during ATP depletion and recovery.
The American journal of physiology - 1 Jun 1999
Raman N, Atkinson S J
Abstract excerpt
Actin cytoskeletal disruption is a hallmark of ischemic injury and ATP depletion in a number of cell types, including renal epithelial cells. We manipulated Rho GTPase signaling by transfection and microinjection in LLC-PK proximal tubule epithelial cells and observed actin cytoskeletal organization following ATP depletion or recovery by confocal microscopy and quantitative image analysis. ATP depletion resulted...
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