Rho controls actin cytoskeletal assembly in renal epithelial cells during ATP depletion and recovery.

doi:10.1152/ajpcell.1999.276.6.C1312

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Rho controls actin cytoskeletal assembly in renal epithelial cells during ATP depletion and recovery.

The American journal of physiology - 1 Jun 1999

Raman N, Atkinson S J

Abstract excerpt

Actin cytoskeletal disruption is a hallmark of ischemic injury and ATP depletion in a number of cell types, including renal epithelial cells. We manipulated Rho GTPase signaling by transfection and microinjection in LLC-PK proximal tubule epithelial cells and observed actin cytoskeletal organization following ATP depletion or recovery by confocal microscopy and quantitative image analysis. ATP depletion resulted...

Topics

ADP Ribose Transferases
Actins
Adenosine Triphosphate
Animals
Botulinum Toxins
Cytoskeletal Proteins
Cytoskeleton
Cytosol
Epithelial Cells
GTP Phosphohydrolases
Genes, Dominant
Kidney
Kidney Cortex
LLC-PK1 Cells
Microinjections
Mutation
Paxillin
Phosphoproteins

Source

Open in PubMed

Identifiers

PMID: 10362594
DOI: 10.1152/ajpcell.1999.276.6.C1312

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics