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Article

Rho GTPase signaling modulates cell shape and contractile phenotype in an isoactin-specific manner.

American journal of physiology. Cell physiology - 1 Nov 2003

Kolyada Alexey Y, Riley Kathleen N, Herman Ira M

Abstract excerpt

Rho family small GTPases (Rho, Rac, and Cdc42) play an important role in cell motility, adhesion, and cell division by signaling reorganization of the actin cytoskeleton. Here, we report an isoactin-specific, Rho GTPase-dependent signaling cascade in cells simultaneously expressing smooth muscle and nonmuscle actin isoforms. We transfected primary cultures of microvascular pericytes, cells related to vascular...

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Identifiers

PMID: 14532019
DOI: 10.1152/ajpcell.00177.2003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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