Article

Mechanical stretch disrupts intracellular structures under impaired actin integrity in vascular smooth muscle cells

2026-05-20

Abstract excerpt

Actin-bundle organization is essential for vascular smooth muscle cell mechanics and is implicated in actin-related diseases. However, it remains unclear how cell stretching affects intracellular actin bundles when actin polymerization is impaired. Here, we performed live imaging of Latrunculin A-treated A7r5 vascular smooth muscle cells in a stretch chamber. GFP– α -actinin imaging showed that Latrunculin A redu...

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Literature Corpus work: acb9a127-5427-5e73-a5cc-3310940d86a3
DOI: 10.64898/2026.05.17.725699

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