Article
Actin-based cytoskeleton regulates a chloride channel and cell volume in a renal cortical collecting duct cell line.
1 Mar 1994
Abstract excerpt
The regulatory volume decrease (RVD) of a renal cortical collecting duct cell line (RCCT-28A) exposed to a hypotonic solution was studied using electronic cell sizing to measure cell volume and the patch clamp technique to measure Cl- channel activity. Results demonstrate that RVD was mediated in part by KCl loss through separate K+ and Cl- channels. The Cl- channel had a conductance of 305 pS and was activated...
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