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Article

Role of Cingulin in Agonist-induced Vascular Endothelial Permeability.

The Journal of biological chemistry - 4 Nov 2016

Tian Yufeng, Gawlak Grzegorz, Tian Xinyong, Shah Alok S, Sarich Nicolene, Citi Sandra, Birukova Anna A

Abstract excerpt

Agonist-induced activation of Rho GTPase signaling leads to endothelial cell (EC) permeability and may culminate in pulmonary edema, a devastating complication of acute lung injury. Cingulin is an adaptor protein first discovered in epithelium and is involved in the organization of the tight junctions. This study investigated the role of cingulin in control of agonist-induced lung EC permeability via interaction...

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Identifiers

PMID: 27590342
DOI: 10.1074/jbc.M116.720763
PMCID: PMC5095421

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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