Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Small GTP-binding Protein Rho Regulates Cortical Activities in Cultured Cells during Division

25 Jan 1999

Abstract excerpt

We have investigated the role of the small GTP-binding protein Rho in cytokinesis by microinjecting an inhibitor, C3 ribosyltransferase, into cultured cells. Microinjection of C3 into prometaphase or metaphase normal rat kidney epithelial cells induced immediate and global cortical movement of actin toward the metaphase plate, without an apparent effect on the mitotic spindle. During anaphase, concentrated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Kidney Cyst Diseases
Share to Microtubule and mitosis dynamics
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9922456
DOI: 10.1083/jcb.144.2.305

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Small GTP-binding Protein Rho Regulates Cortical Activities in Cultured Cells during DivisionPMID 9922456Read ↗

MgcRacGAP regulates cortical activity through RhoA during cytokinesis.Semantic proximity Read ↗

Microinjection of recombinant p21rho induces rapid changes in cell morphology.Semantic proximity Read ↗

Inhibition of cyclin-dependent kinase 1 induces cytokinesis without chromosome segregation in an ECT2 and MgcRacGAP-dependent manner.Semantic proximity Read ↗

Polarization and Migration of Hematopoietic Stem and Progenitor Cells Rely on the RhoA/ROCK I Pathway and an Active Reorganization of the Microtubule NetworkSemantic proximity Read ↗

Rho-stimulated contractility contributes to the fibroblastic phenotype of Ras-transformed epithelial cells.Semantic proximity Read ↗

p190RhoGAP is cell cycle regulated and affects cytokinesis.Semantic proximity Read ↗

A role for Dictyostelium racE in cortical tension and cleavage furrow progression.Semantic proximity Read ↗

Cell type-specific regulation of RhoA activity during cytokinesis.Semantic proximity Read ↗

Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior.Semantic proximity Read ↗

Non-junctional role of Cadherin3 in cell migration and contact inhibition of locomotion via domain-dependent, opposing regulation of Rac1.Semantic proximity Read ↗

The small GTPase Rho mediates articular chondrocyte phenotype and morphology in response to interleukin-1alpha and insulin-like growth factor-I.Semantic proximity Read ↗

Ect2 and MgcRacGAP regulate the activation and function of Cdc42 in mitosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.