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Article

Genetic analysis of late-onset type 2 diabetes in a mouse model of human complex trait.

1 May 1999

Abstract excerpt

Type 2 diabetes is a complex trait with both genes and environmental factors contributing to susceptibility. Except for rare subtypes with monogenic inheritance, the genetic basis of type 2 diabetes is unknown because of the complex and heterogeneous nature of the disease. By using the NSY mouse, an inbred mouse model of type 2 diabetes, we genetically dissected late-onset type 2 diabetes and demonstrated...

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Identifiers

PMID: 10331425
DOI: 10.2337/diabetes.48.5.1168

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