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Article

Novel susceptibility gene for late-onset NIDDM is localized to human chromosome 12q.

Diabetes - 1 Nov 1998

Shaw J T, Lovelock P K, Kesting J B, Cardinal J, Duffy D, Wainwright B, Cameron D P

Abstract excerpt

NIDDM has a substantial genetic component, but the nature of the genetic susceptibility is largely unknown. Maturity-onset diabetes of the young (MODY) is a genetically heterogeneous monogenic form of NIDDM characterized by an early age of onset and autosomal dominant inheritance, and linkage studies have identified genes that are mutated in different MODY pedigrees on chromosome 20 (MODY1 locus, hepatocyte...

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PMID: 9792550
DOI: 10.2337/diabetes.47.11.1793

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Novel susceptibility gene for late-onset NIDDM is localized to human chromosome 12q.PMID 9792550Read ↗

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New susceptibility locus for NIDDM is localized to human chromosome 20q.Semantic proximity Read ↗

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Genetic modifiers of the age at diagnosis of diabetes (MODY3) in carriers of hepatocyte nuclear factor-1alpha mutations map to chromosomes 5p15, 9q22, and 14q24.Semantic proximity Read ↗

Novel mutations and a mutational hotspot in the MODY3 gene.Semantic proximity Read ↗

Localization of MODY3 to a 5-cM region of human chromosome 12.Semantic proximity Read ↗

Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)Semantic proximity Read ↗

Identification of nine novel mutations in the hepatocyte nuclear factor 1 alpha gene associated with maturity-onset diabetes of the young (MODY3).Semantic proximity Read ↗

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