E96V Mutation in the Kdelr3 Gene Is Associated with Type 2 Diabetes Susceptibility in Obese NZO Mice.

doi:10.3390/ijms24010845

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Article

E96V Mutation in the Kdelr3 Gene Is Associated with Type 2 Diabetes Susceptibility in Obese NZO Mice.

International journal of molecular sciences - 3 Jan 2023

Altenhofen Delsi, Khuong Jenny Minh-An, Kuhn Tanja, Lebek Sandra, Görigk Sarah, Kaiser Katharina, Binsch Christian, Griess Kerstin, Knebel Birgit, Belgardt Bengt-Frederik, Cames Sandra, Eickelschulte Samaneh, Stermann Torben, Rasche Axel, Herwig Ralf, Weiss Jürgen, Vogel Heike, Schürmann Annette, Chadt Alexandra, Al-Hasani Hadi

Abstract excerpt

Type 2 diabetes (T2D) represents a multifactorial metabolic disease with a strong genetic predisposition. Despite elaborate efforts in identifying the genetic variants determining individual susceptibility towards T2D, the majority of genetic factors driving disease development remain poorly understood. With the aim to identify novel T2D risk genes we previously generated an N2 outcross population using the two...

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PMID: 36614300
DOI: 10.3390/ijms24010845
PMCID: PMC9820861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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