Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Diet-induced gene expression of isolated pancreatic islets from a polygenic mouse model of the metabolic syndrome

9 Nov 2009

Abstract excerpt

AIMS/HYPOTHESIS: Numerous new genes have recently been identified in genome-wide association studies for type 2 diabetes. Most are highly expressed in beta cells and presumably play important roles in their function. However, these genes account for only a small proportion of total risk and there are likely to be additional candidate genes not detected by current methodology. We therefore investigated islets from...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes and associated disorders
Share to Genetic Associations and Epidemiology
Share to Pancreatic function and diabetes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19902174
DOI: 10.1007/s00125-009-1576-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Diet-induced gene expression of isolated pancreatic islets from a polygenic mouse model of the metabolic syndromePMID 19902174Read ↗

Differential transcriptome analysis of diabetes-resistant and -sensitive mouse islets reveals significant overlap with human diabetes susceptibility genes.Semantic proximity Read ↗

Nutrition-/diet-induced changes in gene expression in pancreatic β-cells.Semantic proximity Read ↗

Genetic Drivers of Pancreatic Islet Function.Semantic proximity Read ↗

Diabetes genes identified by genome-wide association studies are regulated in mice by nutritional factors in metabolically relevant tissues and by glucose concentrations in islets.Semantic proximity Read ↗

The single-cell RNA sequencing (scRNA-seq) transcriptome profile of pancreatic islets in three types of diabetic mice and its pathological changesSemantic proximity Read ↗

Gene expression analysis reveals diabetes-related gene signaturesSemantic proximity Read ↗

Expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion.Semantic proximity Read ↗

Proteomic pathways to metabolic disease and type 2 diabetes in the pancreatic isletSemantic proximity Read ↗

Clusters of conserved beta cell marker genes for assessment of beta cell phenotype.Semantic proximity Read ↗

Identification of Novel Genes Involved in Hyperglycemia in Mice.Semantic proximity Read ↗

Transcriptomic heterogeneity of non-beta islet cells is associated with type 2 diabetes development in mouse modelsSemantic proximity Read ↗

Causal network perturbation analysis identifies known and novel type-2 diabetes driver genesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.