Article
Novel loci for hyperglycemia identified by QTL mapping of longitudinal phenotypes and congenic analysis.
Scientific reports - 24 Jan 2023
Babaya Naru, Itoi-Babaya Michiko, Ueda Hironori, Kobayashi Misato, Noso Shinsuke, Hiromine Yoshihisa, Ishikawa Akira, Fujisawa Tomomi, Ikegami Hiroshi
Abstract excerpt
We previously reported that four hyperglycemia loci are located on three chromosomes in the Nagoya-Shibata-Yasuda (NSY) mouse model, commonly used to study type 2 diabetes. However, we did not search for hyperglycemia loci across all chromosomes. In this study, we performed quantitative trait loci (QTLs) mapping of longitudinal phenotypes from crosses between NSY (hyperglycemic) and C3H (normoglycemic) mice. We...
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