Article

An Association of CSF Apolipoprotein E glycosylation and amyloid-beta 42 in individuals who carry the APOE4 allele

2022-09-01

Abstract excerpt

Carrying the Apolipoprotein E (apoE) ε4 allele is associated with an increased risk of cerebral amyloidosis, but the degree to which apoE glycosylation affects its development is not clear. In a previous pilot study, we identified distinct total and secondary isoform-specific cerebral spinal fluid (CSF) apoE glycosylation profiles, with the apoE4 isoform having the lowest glycosylation percentage (E2 > E3 > E4). I...

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Literature Corpus work: ffbeae4c-c14b-581e-adb7-d2cab298028c
DOI: 10.21203/rs.3.rs-2003074/v1

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