Article

Apolipoprotein E O-glycosylation is associated with amyloid plaques and <i>APOE</i> genotype

2023-01-03

Abstract excerpt

<h4>ABSTRACT</h4> Although the APOE ε4 allele is the strongest genetic risk factor for sporadic Alzheimer’s disease (AD), the relationship between apolipoprotein (apoE) and AD pathophysiology is not yet fully understood. Relatively little is known about the apoE protein species, including post-translational modifications, that exist in the human periphery and CNS. To better understand these apoE species, we deve...

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Literature Corpus work: 225560e0-89dd-5627-b829-1a6cf3fdf6ab
DOI: 10.1101/2023.01.03.522616

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