Article

Deaminase-based RNA recording enables high throughput mutational profiling of protein-RNA interactions

2025-04-12

Abstract excerpt

Protein-RNA interactions govern nearly every aspect of RNA metabolism and are frequently dysregulated in disease. While individual protein residues and RNA nucleotides critical for these interactions have been characterized, scalable methods that jointly map protein- and RNA-level determinants remain limited. RNA deaminase fusions have emerged as a powerful strategy to identify transcriptome-wide targets of RNA-bi...

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Literature Corpus work: ff35c4b2-628a-529c-884f-a7fbbac041e6
DOI: 10.1101/2025.04.11.648485

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