Article

NETosis and Myeloperoxidase Promotes Inflammation and Cardiac Remodeling in Arrhythmogenic Cardiomyopathy

2026-04-17

Abstract excerpt

<h4>Background</h4> Arrhythmogenic cardiomyopathy (ACM) is a heritable nonischemic cardiomyopathy and a leading cause of sudden cardiac death. Although inflammation is a pathological hallmark of ACM, the contribution of peptidylarginine deiminase 4 (PAD4)-dependent neutrophil extracellular trap (NET) formation and myeloperoxidase (MPO) to disease progression remains poorly defined. <h4>Methods</h4> To define the...

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Literature Corpus work: ff063108-0232-5f88-9bfc-3b5343785aa2
DOI: 10.64898/2026.04.14.718596

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