Article

Early cardiac inflammation as a driver of murine model of Arrhythmogenic Cardiomyopathy

2020-06-26

Abstract excerpt

The study of a desmoglein 2 murine model of arrhythmogenic cardiomyopathy revealed cardiac inflammation as a key early event leading to fibrosis. Arrhythmogenic Cardiomyopathy (AC) is an inherited heart muscle disorder leading to ventricular arrhythmias and heart failure due to abnormalities in the cardiac desmosome. We examined how loss of desmoglein 2 ( Dsg2 ) in the young murine heart leads to development of A...

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Literature Corpus work: b8a5458e-54a5-5174-aba7-f968a94b9c09
DOI: 10.1101/2020.06.24.169664

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