Article

Interleukin-1β Drives Disease Progression in Arrhythmogenic Cardiomyopathy

2024-12-17

Abstract excerpt

Arrhythmogenic cardiomyopathy (ACM) is a genetic form of heart failure that affects 1 in 5000 people globally and is caused by mutations in cardiac desmosomal proteins including PKP2, DSP , and DSG2. Individuals with ACM suffer from ventricular arrhythmias, sudden cardiac death, and heart failure. There are few effective treatments and heart transplantation remains the best option for many affected individuals....

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Identifiers and source

Literature Corpus work: 69651aa2-3876-53e9-a32c-099a0bd590ff
DOI: 10.1101/2024.12.11.628020

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