Article

Molecular architecture of human atherosclerosis revealed through integrative human genetics

2025-03-07

Abstract excerpt

<h4>ABSTRACT</h4> Current genetic discovery methods are largely restricted to profiling circulating molecules or genetic architecture, limited in use of tissue-based molecular genetics to identify pathogenic and therapeutic targets. Here, we leverage a multi-level genetic discovery platform integrating population-level proteomics with functional genomic analyses based on human coronary artery tissue to reveal dete...

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Literature Corpus work: fef9f6c8-353d-54b0-9860-7f9be0e5babd
DOI: 10.1101/2025.03.06.25323506

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