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Article

Proteogenomic Analysis of Coronary Artery Calcification in Human Populations.

Arteriosclerosis, thrombosis, and vascular biology - 1 Jun 2026

El-Sabawi Bassim, Huang Xiaoning, Lin Phillip, Anwar Mohammad Yaser, Betti Michael, Kim Namju, Perry Andrew S, Perera B Lakshitha A, Gajjar Priya, Colangelo Laura A, Amancherla Kaushik, Sheng Quanhu, Zhao Shilin, Stolze Lindsay K, Farber-Eger Eric, Landman Joshua M, Miller Patricia E, Liu Gabrielle Y, Das Suman, Wells Quinn S, Terry James G, Lloyd-Jones Donald, Das Saumya, Khan Sadiya S, North Kari E, Below Jennifer, Nayor Matthew, Kalhan Ravi, Carr John Jeffrey, Gamazon Eric R, Shah Ravi V

Abstract excerpt

BACKGROUND: Joint use of multiple molecular layers can be useful to prioritize targets for mechanistic studies. Application of this approach to coronary disease in large populations is an emerging field. METHODS: We used reported circulating proteomic data (Somascan aptamer-based) from ≈3000 individuals in the CARDIA study (Coronary Artery Risk Development in Young Adults), measuring association with prevalent...

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Source

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Identifiers

PMID: 41924874
DOI: 10.1161/ATVBAHA.125.324171
PMCID: PMC13156906

Genes

APOC1
ARHGAP36
CDCP1
CILP2
GIP
GSN
HES1
NOTCH3
PCSK9
S100A12
S100A9
SPARC
SPARCL1
THBS2
TNFSF12

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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